Translating Mouse Models
نویسندگان
چکیده
منابع مشابه
Pancreatic cancer: translating lessons from mouse models.
Pancreatic cancer is the 10th most common cancer and 4th cause of cancer related deaths. Progress in diagnosis and treatment has been slow and disappointing but improvement in understanding of pathogenesis and of molecular changes may offer some ground for rational and etiological approach. During the last ten years the first evidence about the benefit of targeting dysregulated pathways was pro...
متن کاملPancreatic cancer: translating lessons from mouse models and hereditary syndromes.
Pancreatic ductal adenocarcinoma is the overwhelmingly predominant form of pancreatic cancer and the second most common type of gastrointestinal cancer (behind colorectal cancer) in the United States. Recent exciting advances in two areas of pancreatic ductal adenocarcinoma (i.e., the development and characterization of genetically engineered mouse models and the dissection of the genetic basis...
متن کاملTranslating insights of AR signaling from mouse models
Androgen receptor (AR) signaling plays a critical role in the physiology of the prostate and thus the biology of prostate cancer. Agents targeting the AR pathway have been the mainstay of treatment for patients with locally advanced and metastatic prostate cancer. In this review we will cover the role of androgen signaling in prostate cancer mouse models with an emphasis on how tumorigenic mole...
متن کاملTranslating IS Models into Practice
Enterprise resource planning (ERP) systems have emerged as the core element of the application infrastructure of organisations around the globe. It has been interesting to observe that the related IS research was very much driven by practice. Only after a time lag was the IS community able to catch up with practical challenges. ERP systems provide many opportunities to apply established IS mode...
متن کاملTranslating between Horn Representations and Their Characteristic Models Translating between Horn Representations and Their Characteristic Models
Characteristic models are an alternative, model based, representation for Horn expressions. It has been shown that these two representations are incomparable and each has its advantages over the other. It is therefore natural to ask what is the cost of translating , back and forth, between these representations. Interestingly, the same translation questions arise in database theory, where it ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 2016
ISSN: 0192-6233,1533-1601
DOI: 10.1177/0192623316675767